There are many types of medicine-packed syringe product […]
There are many types of medicine-packed syringe products on the syringe assembly machine market, and the quality is different, so how can we correctly identify the quality of medicine-packed syringe products? Now do the following brief analysis based on some of its characteristics:
First of all, the current medicine packaging syringes are mainly made of glass and plastic materials.
Plastic infusion devices are gradually replacing glass syringes, which mainly have lower cost, higher safety than glass syringes, and are not easy to break. The production process of the device products is relatively advanced. Generally speaking, the injection process is used to produce the syringe. The products produced by the injection molding process are formed at one time, without scraps, the product size is accurate, and the weight is uniform.
Second, the tightness requirements of syringe products are high.
When selecting a syringe, it should be tested for its tightness. Inject half of the water into the syringe, insert the piston into the syringe, remove the protective cap, and remove the residual air. Block with a protective cap, and apply an axial pressure of 30N on the plunger plug inside the barrel through the push rod for 30 seconds. There should be no leakage at the seal of the protective cap and the piston.
Third, the syringes must ensure their sterility due to direct contact with drugs.
Generally, syringes should be produced in clean workshops that meet national standards. In addition, in order to ensure their sterility, if the veterinary drug manufacturer has a high sterility On request, additional ethylene oxide sterilization or cobalt 60 irradiation sterilization can be performed.
The pre-filled syringe is an advanced medical liquid container, which can be used as both a container and a syringe. The pre-filled syringe is mainly composed of a tube sleeve, a push rod, a positioning ring, and a piston. The push rod of the pre-filled syringe can be printed with a scale, which can be used more accurately. Because of its convenient use, flexible medication, and the ability to fill the liquid in advance, it is gradually favored by the majority of pharmaceutical companies.
The standard rubber stopper for pre-filled syringes is bromobutyl or chlorobutyl, and is generally used for routine occasions without special requirements. If the product reacts with the rubber stopper or in the case where the free silicone oil needs to be minimized, it is necessary to use a special part or all of the PTFE-coated rubber stopper, or even the PTFE rubber stopper. The choice of rubber plug is very important, and it also greatly affects the choice of plug method. When choosing a rubber plug, you need to consider the following factors:
1. The price of the rubber plug;
2. The interaction between the product and the rubber plug;
3. Reduce the amount of free silicone oil (depending on the type of coating, the amount of free silicone may be reduced and the extrusion effect will be reduced);
4. The risk of particles during the plugging process;
5. The compressibility of the rubber plug without damage to the coating or appearance defects.
The standard rubber stopper has the lowest price, but its stability is not as good as PTFE. The contact surface of the coated rubber plug has less free silicon. If pre-filled syringes must reduce free silicone oil or need to improve barrier conditions, coated rubber plugs are often selected.
